RESUMO
Myxofibrosarcoma is recognized as a malignant neoplasm of fibroblastic origin with increased prevalence in the elderly, presenting as nodules or tumors that may extend to the dermis and skeletal muscle, preferably in the lower limbs. Histologically it is characterized by a proliferation of spindle cells in a myxoid stroma. Myxofibrosarcoma has a high potential for local recurrence and metastasis, mainly when it presents a high or intermediate histological grade. We report the case of an eighty-four year old patient with a difficult diagnosis of a highly aggressive tumor.
Assuntos
Fibroma/patologia , Mixossarcoma/patologia , Neoplasias Cutâneas/patologia , Idoso de 80 Anos ou mais , Biópsia , Humanos , Imuno-Histoquímica , Metástase Linfática , Imageamento por Ressonância Magnética , Masculino , Recidiva Local de Neoplasia , Pele/patologiaRESUMO
Abstract Myxofibrosarcoma is recognized as a malignant neoplasm of fibroblastic origin with increased prevalence in the elderly, presenting as nodules or tumors that may extend to the dermis and skeletal muscle, preferably in the lower limbs. Histologically it is characterized by a proliferation of spindle cells in a myxoid stroma. Myxofibrosarcoma has a high potential for local recurrence and metastasis, mainly when it presents a high or intermediate histological grade. We report the case of an eighty-four year old patient with a difficult diagnosis of a highly aggressive tumor.
Assuntos
Humanos , Masculino , Idoso de 80 Anos ou mais , Neoplasias Cutâneas/patologia , Fibroma/patologia , Mixossarcoma/patologia , Pele/patologia , Biópsia , Imuno-Histoquímica , Imageamento por Ressonância Magnética , Metástase Linfática , Recidiva Local de NeoplasiaRESUMO
The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this disease. We present a case of a male, 12 year old healthy patient who, five days after Influenza vaccination, developed erythematous papules on the trunk, abdomen and limbs, some with adherent crusts and associated systemic symptoms. This case report is notable for describing the first case of pityriasis lichenoides et varioliformis acuta associated with the vaccine against Influenza.
Assuntos
Vacinas contra Influenza/efeitos adversos , Pitiríase Liquenoide/etiologia , Criança , Epiderme/patologia , Eritema/tratamento farmacológico , Eritema/etiologia , Eritema/patologia , Humanos , Masculino , Pitiríase Liquenoide/tratamento farmacológico , Pitiríase Liquenoide/patologiaRESUMO
The etiology of pityriasis lichenoides is unknown. One of the accepted theories admits that PL is an inflammatory response to extrinsic antigens such as infectious agents, drugs and vaccines. In recent medical literature, only the MMR vaccine (Measles, Mumps and Rubella) was associated with the occurrence of this disease. We present a case of a male, 12 year old healthy patient who, five days after Infl uenza vaccination, developed erythematous papules on the trunk, abdomen and limbs, some with adherent crusts and associated systemic symptoms. This case report is notable for describing the first case of pityriasis lichenoides et varioliformis acuta associated with the vaccine against Influenza.
.Assuntos
Criança , Humanos , Masculino , Vacinas contra Influenza/efeitos adversos , Pitiríase Liquenoide/etiologia , Epiderme/patologia , Eritema/tratamento farmacológico , Eritema/etiologia , Eritema/patologia , Pitiríase Liquenoide/tratamento farmacológico , Pitiríase Liquenoide/patologiaRESUMO
Brazil is a country of continental dimensions with a large heterogeneity of climates and massive mixing of the population. Almost the entire national territory is located between the Equator and the Tropic of Capricorn, and the Earth axial tilt to the south certainly makes Brazil one of the countries of the world with greater extent of land in proximity to the sun. The Brazilian coastline, where most of its population lives, is more than 8,500 km long. Due to geographic characteristics and cultural trends, Brazilians are among the peoples with the highest annual exposure to the sun. Epidemiological data show a continuing increase in the incidence of non-melanoma and melanoma skin cancers. Photoprotection can be understood as a set of measures aimed at reducing sun exposure and at preventing the development of acute and chronic actinic damage. Due to the peculiarities of Brazilian territory and culture, it would not be advisable to replicate the concepts of photoprotection from other developed countries, places with completely different climates and populations. Thus the Brazilian Society of Dermatology has developed the Brazilian Consensus on Photoprotection, the first official document on photoprotection developed in Brazil for Brazilians, with recommendations on matters involving photoprotection.
Assuntos
Humanos , Proteção Radiológica/métodos , Queimadura Solar/prevenção & controle , Protetores Solares/administração & dosagem , Dermatopatias/prevenção & controle , Neoplasias Cutâneas/prevenção & controle , Neoplasias Cutâneas/epidemiologia , Energia Solar/estatística & dados numéricos , Queimadura Solar/epidemiologia , Protetores Solares/química , Raios Ultravioleta/efeitos adversos , Vitamina D/metabolismo , Brasil/epidemiologia , Vestuário , Exposição Ambiental , Radiação Eletromagnética , Promoção da Saúde/métodos , Conceitos MeteorológicosRESUMO
Brazil is a country of continental dimensions with a large heterogeneity of climates and massive mixing of the population. Almost the entire national territory is located between the Equator and the Tropic of Capricorn, and the Earth axial tilt to the south certainly makes Brazil one of the countries of the world with greater extent of land in proximity to the sun. The Brazilian coastline, where most of its population lives, is more than 8,500 km long. Due to geographic characteristics and cultural trends, Brazilians are among the peoples with the highest annual exposure to the sun. Epidemiological data show a continuing increase in the incidence of non-melanoma and melanoma skin cancers. Photoprotection can be understood as a set of measures aimed at reducing sun exposure and at preventing the development of acute and chronic actinic damage. Due to the peculiarities of Brazilian territory and culture, it would not be advisable to replicate the concepts of photoprotection from other developed countries, places with completely different climates and populations. Thus the Brazilian Society of Dermatology has developed the Brazilian Consensus on Photoprotection, the first official document on photoprotection developed in Brazil for Brazilians, with recommendations on matters involving photoprotection.
